Welcome to VacCAP for All. Here you can find a collection of VacCAP research summarized into accessible, everyday language.

Graduate student Yurah Kim evaluating organic acid HPLC profiles in a progeny (family) segregating for the low malic acid geneA Low Malic Acid Trait in Cranberry Fruit: Genetics, Molecular Mapping, and Interaction With a Citric Acid Locus

To offset the tartness for consumers, higher amounts of sugar need to be added in the cranberry products, such as sweetened-dried-cranberries and juices. The added sugar has deterred consumers from increasing cranberry product consumption despite cranberry health benefits.

Within the cranberry germplasm collection at Rutgers University, a unique cranberry plant was identified with fruit having a lower percent TA than is normally found in commercial cultivars and may offer cranberry products with less added sugar. Crosses using this plant identified a naturally occurring genetic trait that produced fruit with a lower malic acid, which impacts TA.

Utilizing these populations—segregating for the low malic acid traits—it was possible to generate effective genetic markers for use in breeding of cranberry cultivars with TA. Read more

The American cranberry (Vaccinium macrocarpon Ait.) genome multidimensional landscape. Fruit and flower photos by Fernando De la Torre and Eric Wiesman

Piecing Together the Cranberry Genome Puzzle

Over the last decade, Dr. Juan Zalapa has been working on a puzzle—a 500-million-piece one. Zalapa and others in his team—such as Luis Diaz-Garcia—is working to assemble the ‘Stevens’ cranberry genome in order to identify which genes control what traits in cranberry cultivars. 

“Cranberries have 12 chromosomes. So, one of the things that we need to do for sequencing is to decipher the genetic code (bases) of those 12 chromosomes,” Zalapa said “When you do any kind of genetic sequencing, you can't get a single piece sequence for a whole chromosome. There are 500 million bases of chromosome sequence—divided into 12 chromosomes roughly, it could be 50 million bases per chromosome. And assembling this is like putting together a puzzle.” Read more